Liposuction Research Today is a free monthly online journal that collates and summarizes the latest research about Liposuction, including details on surgery, procedure, cellulite, alternatives. | ||||||||
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Histologic effects of external ultrasound-assisted lipectomy on adipose tissue.Ferraro GA, De Francesco F, Nicoletti G, Rossano F, D'Andrea F Department of Orthopedic, Traumatologic, Rehabilitative, and Plastic Reconstructive Sciences, Second University of Naples, School of Medicine and Surgery, via L. De Crecchio 3, 80138, Napoli, Italy, giuseppe.ferraro@unina2.it. This study aimed to observe the effects of ultrasound waves at different frequencies on abdominal fat tissue. External ultrasound-assisted lipectomy (XUAL) via both histologic and immunohistochemic examinations was used to assess adipose tissue alterations, including cells and collagenic fibers. The results, at the immunofluorescence level, show that ultrasound used at 1 MHz with a potency of 3 W resulted in no alterations or only limited cell destruction with collagen fibers intact. In contrast, when the ultrasound was 2 and especially 3 MHz, adipocyte alterations usually were evident. Massive adipose tissue destruction, confirmed using Oil red-O staining, was observed. In addition, at the immunofluorescence level, diffuse collagen fiber retraction was detected. This was particularly evident in comparisons with biopsies of intact control samples, which showed normal adipose tissue and intact collagen fibers. The results obtained using morphologic techniques, which do not allow fixation artifacts and include collagen observations, demonstrate that with the XUAL technique, ultrasound at 1 MHz does not induce cellular alterations. In contrast, both 2- and 3-MHz frequencies are capable of causing complete fat tissue disruption, including destruction of adipose cells and collagenic fibers. Published 7 January 2008 in Aesthetic Plast Surg, 32(1): 111-5.
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